Automated Edman sequencing is a classical technique used to determine the primary structure of peptides and proteins. The PCL proudly still offers this service to TAMU and non-TAMU scientists. The technique is invaluable in providing direct amino acid sequence information. Our instrumentation provides quantitative amino acid sequence solely from the amino terminus of the protein/peptide. This is a useful approach for validating correct processing of amino termini when unavailable from mass spec analysis.